I’m due to start on Venetoclax next week and escalating the dose up to the full 400mg/day will take 5 weeks. Venetoclax is new, so new that I’m the first patient at Frimley Park to take it. So they’re being ultra cautious, and I have to be admitted to be monitored for the first doses and the early escalations. Tumour Lysis Syndrome is one of the major side-effects and that is nasty. Hopefully when I’m stabilised on a suitable dose the other side effects will be tolerable because I’ve got used to feeling good in the past 7 weeks since I stopped Ibrutinib. I’ve been propped up by daily injections of a synthetic bone marrow stimulant which is effective but can’t be used long-term.
So I apologise if I disappear for a month or so while I’m getting used to this new stuff. I hope to reappear in March and get to Eastercon and maybe a Southampton match or two (though given their current form I’m not sure I want to see them).
The current work-in-progress is trundling along and I hope to have a finished first draft this year.